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The Role of the Essential Fatty Acids (Omega-3s)
  • Given the right balance of Omega-6 fatty acids and Omega-3 fatty acids, the body's enzymes preferentially convert the essential fatty acids into the "good" prostaglandins.
  • The Standard American Diet (SAD) or Western diet contains about 25 times more Omega-6 fatty acids than Omega-3 fatty acids. The ratio should be closer to 2.5 to 1.
  • Prostaglandins (PG)  are shot-lived, hormone-like chemicals that regulate cellular activities on a moment-to-moment basis. 
  • PGs are made due to the enzyme-controlled oxidation of highly unsaturated fatty acids.
  • The precision of enzyme-controlled oxidation varies significantly from the random oxidation of fatty acids in air.

Prostaglandins fall into 3 series- PG1, PG-2 and PG3. Series 1 & 2 are produced from Omega-6 (Linoleic Acid or LA), while Series 3 is produced from Omega-3 (alpha-linolenic acid or ALA).

The following tables lists the physiological effects of Series 1 & 3 prostaglandins (the "Good") and Series 2 prostaglandins (the "Bad").

Series 1 & 3

Series 2

 

 

Increased vasodilation

Increased vasoconstriction

Decreased pain

Increased pain

Increased endurance

Decreased endurance

Enhanced immune system

Immune system suppression

Increased oxygen flow

Decreased oxygen flow

Decrease in cellular proliferation

Increases cellular proliferation

Prevents platelet aggregation

Creates platelet aggregation (clotting)

Dilates airways

Constricts airways

Decreases inflammation

Increases inflammation

 
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